The MuSA is a 1,000,000-euro restructuring and technical organization project brought to fruition thanks to the support of the Regione Toscana, through the funds of the "Patto per lo sviluppo – Area 6th – Distretto lapideo" Marble District Development Agreement and thanks to the contribution of the Fondazione Cassa di Risparmio di Lucca bank foundation.
The feasibility study in 2006 was followed in 2007 by the search and selection of a building to house the project and this was found in an old laboratory owned by the Assindustria Lucca industrialists' association. Then came the drafting of the definitive project and its approval in the summer of 2008 by the Regione Toscana. At the conclusion of the competitive bidding managed by the technical departments of the Province of Lucca, the beginning of 2009 saw the start of the renovation work on the building which ended in July 2010 and was made official by the Certificato di Regolare Esecuzione (Certificate of Regular Execution of Works), issued in January 2011. That moment marks the start of the delicate phase of interior design, assembly and operation of the IT equipment.
The MuSA was inaugurated on 24th May 2012.